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As the world's leading independent organization for children in need, Save the Children has programs in nearly 120 countries, including the United States. Their aim is to inspire breakthroughs in the way the world treats children, and to create immediate and lasting change in their lives by improving their health, education and economic opportunities. In times of acute crisis, Save the Children mobilizes rapid assistance to help children recover from the effects of war, conflict and natural disasters.

Samaritan's Purse is a nondenominational evangelical Christian organization providing spiritual and physical aid to hurting people around the world. Since 1970, Samaritan's Purse has helped meet needs of people who are victims of war, poverty, natural disasters, disease, and famine with the purpose of sharing Gods love through His son, Jesus Christ. The organization serves the church worldwide to promote the Gospel of the Lord Jesus Christ.

Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

The Parkinson’s Foundation makes life better for people with Parkinson’s disease by improving care and advancing research toward a cure. In everything we do, we build on the energy, experience and passion of our global Parkinson’s community.

The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.

We grant the wishes of children with life-threatening medical conditions to enrich the human experience with hope, strength and joy. Based in Phoenix, the Make-A-Wish Foundation® is one of the nation's leading charities, serving children in every community in the United States, Puerto Rico and Guam. With the help of generous donors and approximately 25,000 volunteers nationwide, the Make-A-Wish Foundation grants a wish every 38 minutes, on average. Since our inception in 1980, we have granted more than 226,000 wishes. Visit the Make-A-Wish Foundation of America at www.wish.org (http://www.wish.org) and discover how you can share the power of a wish®.

St. Jude Children's Research Hospital seeks to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of their founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay. St. Jude’s strives to be the world leader in advancing the treatment and prevention of catastrophic diseases in children, by providing outstanding patient care; conducting basic, translational and clinical research designed to elucidate biological mechanisms, understand disease pathogenesis, improve diagnosis, enhance treatment outcome, prevent diseases and minimize adverse consequences of treatment; and by educating health care and scientific research professionals. Treatments invented at St. Jude have helped push the overall childhood cancer survival rate from 20% to more than 80% since it opened more than 50 years ago.

Chartered in 1934, the Animal Defense League of Texas (ADL) is the oldest no-kill shelter for abandoned, abused, or neglected dogs and cats in South Central Texas. Through the operation of two facilities, a centrally located 12-acre campus and the city-owned Paul Jolly Center for Adoptions, ADL saves the lives of vulnerable animals primarily originating from the most poverty-stricken communities in San Antonio. A full veterinary hospital housed on the main campus provides spay/neuter surgeries, vaccinations, and microchipping for all pets in ADL’s care. In addition, ADL performs specialized surgeries for animals with complex medical conditions and is the first organization to provide no-cost mobile wellness clinics to historically underserved areas. ADL’s partnership with Animal Care Services (ACS) is instrumental in helping the City of San Antonio back to achieving a “No-Kill” status.

For over 30 years, Best Friends Animal Society has been running the nation’s largest no-kill sanctuary for companion animals and building effective programs that reduce the number of animals entering shelters. The mission of Best Friends Animal Society is to bring about a time when there are No More Homeless Pets. The organization does this by helping end the killing in America's animal shelters through building community programs and partnerships all across the United States.

Founded in 1947, Dana-Farber Cancer Institute is committed to providing expert, compassionate care to children and adults with cancer, while advancing the understanding, treatment, cure, and prevention of cancer and related diseases. As an affiliate of Harvard Medical School and a Comprehensive Cancer Center designated by the National Cancer Institute, the Institute also provides training for new generations of physicians and scientists, designs programs that promote public health particularly among high-risk and underserved populations and disseminates innovative patient therapies and scientific discoveries in Boston, across the United States and throughout the world.

Our mission is to be a relentless force in building a world of strong, healthier lives, free of cardiovascular diseases and stroke. Our mission drives everything we do. We’re the nation’s leader in CPR education training. We help people understand the importance of healthy lifestyle choices. We provide science-based treatment guidelines to healthcare professionals to help ensure the best treatment for every patient, every time. We educate lawmakers, policy makers and the public as we advocate for changes to protect and improve the health of our communities.