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For over 150 years, the ASPCA has worked tirelessly to put an end to animal abuse and neglect. We are a national leader in the areas of rescue, adoption and welfare, and your tax-deductible donation will help fight cruelty and make a life-changing difference for animals across America. Thank you for making the ASPCA and the animals we serve a part of your life.

In 2015 Charleston Animal Society drew the line and became the first No Kill community in the Southeast. Charleston Animal Society is recognized as a model for shelters all over including France and New Zealand. Getting animal off the streets and having medical funding for the critical cases including Caitlyn's Anti Cruelty fund

Founded in 1868, the mission of the San Francisco SPCA is to save and protect animals, provide care and treatment, advocate for their welfare and enhance the human-animal bond.

The mission of the Massachusetts Society for the Prevention of Cruelty to Animals - Angell Animal Medical Center is to protect animals, relieve their suffering, advance their health and welfare, prevent cruelty, and work for a just and compassionate society.

The mission of the Atlanta Humane Society is to improve animal welfare in the southeastern United States by providing quality animal services including preventative initiatives, education, advocacy and adoption of animals into permanent loving homes.

Dakin Humane Society delivers effective, innovative services that improve the lives of animals in need and the people who care about them.

We transform lives through exceptional animal care, humane education, and advocacy. Every day, we inspire compassion and positive relationships between people and animals.

Guide Dogs for the Blind provides enhanced mobility to qualified individuals through partnership with dogs whose unique skills are developed and nurtured by dedicated volunteers and a professional staff. Established in 1942, Guide Dogs for the Blind continues its dedication to quality student training services and extensive follow-up support for graduates. Our programs are made possible through the teamwork of staff, volunteers and generous donors. Services are provided to students from the United States and Canada at no cost to them.

For 121 years, The Animal Rescue League of Boston (ARL) has responded to the needs of animals and the people who care about them. In fact, we are often the first to respond. With over 520 dedicated volunteers and 100 staff members, ARL lends unwavering support to local animals, families, and neighborhoods. We provide outstanding veterinary care, adoption, and rescue services. We also confront the root causes of animal cruelty and neglect through special police investigation and advocacy aimed at strengthening the laws that protect animals. Last year alone, we served more than 16,000 animals in need.

North Shore Animal League America—the world's largest no-kill rescue and adoption organization—has saved the lives of over 1.1 million dogs, cats, puppies and kittens at risk of euthanasia. Through our many innovative programs, we reach across the country to rescue animals from overcrowded shelters, unwanted litters, puppy mills, natural disasters and other emergencies, rehabilitate them, and find them responsible, loving homes. As a leader in the no-kill movement, we are dedicated to promoting shelter pet adoptions; encouraging spay/neuter programs; reducing animal cruelty; ending euthanasia; and advancing the highest standards in animal welfare.

To save lives, keep families together, and create a better future for pets and their people.

The Humane Society of Missouri offers second chances for abused, neglected and abandoned animals, works to end abuse and pet overpopulation and promotes lasting relationships between animals and people.