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For over 150 years, the ASPCA has worked tirelessly to put an end to animal abuse and neglect. We are a national leader in the areas of rescue, adoption and welfare, and your tax-deductible donation will help fight cruelty and make a life-changing difference for animals across America. Thank you for making the ASPCA and the animals we serve a part of your life.

For over 30 years, Best Friends Animal Society has been running the nation’s largest no-kill sanctuary for companion animals and building effective programs that reduce the number of animals entering shelters. The mission of Best Friends Animal Society is to bring about a time when there are No More Homeless Pets. The organization does this by helping end the killing in America's animal shelters through building community programs and partnerships all across the United States.

Maui Food Bank's mission is to help the hungry in Maui County by collecting and distributing food through community partnerships.

St. Jude Children's Research Hospital seeks to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of their founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay. St. Jude’s strives to be the world leader in advancing the treatment and prevention of catastrophic diseases in children, by providing outstanding patient care; conducting basic, translational and clinical research designed to elucidate biological mechanisms, understand disease pathogenesis, improve diagnosis, enhance treatment outcome, prevent diseases and minimize adverse consequences of treatment; and by educating health care and scientific research professionals. Treatments invented at St. Jude have helped push the overall childhood cancer survival rate from 20% to more than 80% since it opened more than 50 years ago.

The St. Pete Free Clinic's mission is with compassion and respect, St. Pete Free Clinic changes lives by providing health care, nutritious food, recovery housing, and education for our neighbors in need. SPFC’s programs support health equity by providing nutritious food for those who need it, increasing access to healthcare, helping those recovering from substance use with stable housing and support, and educating our community. Your generosity makes all the difference in our capability to serve our neighbors in need.

The mission of Doctors Without Borders/Médecins Sans Frontières (MSF) is to provide impartial medical relief to the victims of war, disease, and natural or man-made disaster, without regard to race, religion, or political affiliation. A non-profit, self-governed, member-based organisation, MSF's global reach is demonstrated by a presence in over 72 countries and territories with medical humanitarian projects, 9,904,200 medical consultations conducted by humanitarian teams, and 877,300 patients admitted to MSF hospitals or clinics around the world.

Chartered in 1934, the Animal Defense League of Texas (ADL) is the oldest no-kill shelter for abandoned, abused, or neglected dogs and cats in South Central Texas. Through the operation of two facilities, a centrally located 12-acre campus and the city-owned Paul Jolly Center for Adoptions, ADL saves the lives of vulnerable animals primarily originating from the most poverty-stricken communities in San Antonio. A full veterinary hospital housed on the main campus provides spay/neuter surgeries, vaccinations, and microchipping for all pets in ADL’s care. In addition, ADL performs specialized surgeries for animals with complex medical conditions and is the first organization to provide no-cost mobile wellness clinics to historically underserved areas. ADL’s partnership with Animal Care Services (ACS) is instrumental in helping the City of San Antonio back to achieving a “No-Kill” status.

The Palestine Children's Relief Fund (PCRF) is a non-political, non-profit organization dedicated to healing the wounds of war, occupation and poverty for children in the Middle East, regardless of their nationality, religion, race or gender.

Americares helps people and communities around the world access health in times of disaster and every day. We are a global health and disaster relief organization that helps people and communities around the world access health in times of disaster and every day. Each year, Americares reaches 80 countries on average, including the United States, with life-changing health programs, medicine, medical supplies and emergency aid. Americares is one of the world’s leading nonprofit providers of donated medicine and medical supplies. For 45 years, we have met the health needs of our local partners and their communities. Our donors make it possible to get medicine and critical care to families and communities in need

Founded in 2010 by Chef José Andrés, World Central Kitchen (WCK) is a nonprofit organization that is first to the frontlines providing fresh meals in response to crises. Applying their model of quick action, leveraging local resources, and adapting in real time, WCK has served more than 400 million nourishing meals around the world. When disaster strikes, WCK’s Relief Team mobilizes with the urgency of now to start cooking and serving meals to people in need. By partnering with organizations on the ground and activating a network of local restaurants, food trucks, or emergency kitchens, WCK serves comforting meals to survivors of disasters quickly and effectively. To support regional economies, WCK prioritizes purchasing local ingredients to cook with or distribute directly to families in need. WCK knows that good food provides not only nourishment, but also comfort and hope, especially in times of crisis. Learn more at wck.org.

The American Red Cross prevents and alleviates human suffering in the face of emergencies by mobilizing the power of volunteers and the generosity of donors. The American Red Cross, through its strong network of volunteers, donors and partners, is always there in times of need. We aspire to turn compassion into action so that all people affected by disaster across the country and around the world receive care, shelter and hope; our communities are ready and prepared for disasters; everyone in our country has access to safe, lifesaving blood and blood products; all members of our armed services and their families find support and comfort whenever needed; and in an emergency, there are always trained individuals nearby, ready to use their Red Cross skills to save lives. The American Red Cross' fundamental principles are: Humanity, Impartiality, Neutrality, Independence, Voluntary Service, Unity, and Universality. Our motto, "You Have the Power to Save a Life" is built upon and reflects such these values.

CARE is a leading humanitarian organization fighting global poverty. We place special focus on working alongside poor women because, equipped with the proper resources, women have the power to help whole families and entire communities escape poverty. Women are at the heart of CARE's community-based efforts to improve basic education, prevent the spread of HIV, increase access to clean water and sanitation, expand economic opportunity and protect natural resources. CARE also delivers emergency aid to survivors of war and natural disasters, and helps people rebuild their lives.