Search Nonprofits

We are a global champion for the human rights of women and girls. We use our powerful networks to find, fund, and amplify the courageous work of women who are building social movements and challenging the status quo. By shining a spotlight on critical issues, we rally communities of advocates who take action and invest money to empower women.

Smile Train is an international children’s charity with a sustainable approach to a single, solvable problem: cleft lip and palate. Millions of children in developing countries with unrepaired clefts live in shame, but more importantly, have difficulty eating, breathing and speaking. Cleft repair surgery is simple, and the transformation is immediate. Our sustainable model provides training and funding to empower local doctors in 85+ developing countries to provide 100%-free cleft repair surgery in their communities. We use the “teach a man to fish” model focusing on training local doctors to perform cleft repairs in their communities. Those doctors then go on to train other doctors creating a long-term, sustainable system. Patients see their smile for the first time, parents cry tears of joy, lives and communities are changed forever. As a result of our efficiency and with the support of our donors and partners around the world, Smile Train has transformed the lives of more than one million children by giving them the power of a smile -- that's roughly 350 surgeries a day and 128,000+ every year.  

We seek out and take in the animals who no other organization will help or would simply euthanize because they are too expensive to heal. We rescue the abandoned, beaten, bred, fought, injured, terrified, defeated and betrayed. The minute they enter our doors, we look in their eyes and promise them ALL the second chance they deserve for health, home, commitment and love, no matter the amount of time or cost involved. Our Vision is to ensure a bright future for the underdog. To end needless suffering, negligence, and abuse. To serve the City of St. Louis and surrounding metro areas and have the largest inner-city animal sanctuary in the country.

The mission of Birthday Wishes is to improve and empower the lives of homeless children and their families by providing joy, play and hope through the magic of a birthday party. Our goal is to ensure that children experiencing the trauma of homelessness have the opportunity to celebrate their birthday joyfully, surrounded by family, friends and others who care.

PROVIDE RESORCES AND CRITICAL INFORMATION We advocate and empower grandparents raising grandchildren by providing access to resources, information and support.

Boot Campaign unites Americans to honor and restore the lives of veterans and their families by providing individualized, life‑improving care. Its programs (including Health & Wellness, Seasons of Service, Lace Up America and You Matter) focus on personalized treatment and support for issues such as PTSD, traumatic brain injury, chronic pain, insomnia and family needs so veterans can improve quality of life.

Operation Breakthrough's mission is to help children who are living in poverty develop to their fullest potential by providing them a safe, loving, and educational environment. The Center also strives to support and empower the children's families through education, advocacy, referral services, and emergency aid.

We equip teen girls with community tools and resources to activate their personal power and world impact through peer leadership, life skills education, mentoring, and youth advocacy.

Oxfam is a global organization that fights inequality to end poverty and injustice. We offer lifesaving support in times of crisis and advocate for economic justice, gender equality, and climate action. We demand equal rights and equal treatment so that everyone can thrive, not just survive. The future is equal.

Project C.U.R.E. was founded in 1987 to help bridge staggering health resource gaps in the developing world by matching medical supplies and modern equipment with facilities in need to empower doctors and nurses with the tools they need to treat disease, deliver vaccines, perform life-changing surgeries and ensure safe childbirth. Project C.U.R.E. operates distribution centers in Colorado, Tennessee, Texas and Arizona and receives donations of supplies and specialized equipment from hundreds of U.S. hospitals and medical manufacturers. Thanks to the dedication of thousands of volunteers nationwide, two to three cargo containers of life-saving aid leave Project C.U.R.E.’s warehouses every week. In addition, Project C.U.R.E. sends volunteer medical teams to underserved facilities abroad to provide free care and train local healthcare staff. Today, Project C.U.R.E. is the world’s largest distributor of medical donations to resource-limited communities across the globe, touching the lives of patients, families and children in 130 countries.

Catholic Relief Services carries out the commitment of the Bishops of the United States to assist the poor and vulnerable overseas. We are motivated by the Gospel of Jesus Christ to cherish, preserve and uphold the sacredness and dignity of all human life, foster charity and justice, and embody Catholic social and moral teaching as we act to: Promote human development by responding to major emergencies, fighting disease and poverty, and nurturing peaceful and just societies; and, Serve Catholics in the United States as they live their faith in solidarity with their brothers and sisters around the world. As part of the universal mission of the Catholic Church, we work with local, national and international Catholic institutions and structures, as well as other organizations, to assist people on the basis of need, not creed, race or nationality.

The mission of United Help Ukraine (UHU) is to provide the people of Ukraine with critical support that will enable them to survive in the face of adversity, to defend and regain their sovereign territory, and to rebuild and thrive well into the future. UHU is committed to maximizing the impact of charitable contributions by providing humanitarian, medical and psychological assistance to those affected by the war. We also focus on raising awareness and advocating for Ukraine to remain a free, democratic and independent nation.