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Prime of life neurodegeneration is a spectrum of relatively rare diseases that often afflict people during productive, active years and lead to debilitating symptoms and early death. They are generally categorized as frontotemporal disorders and are characterized by progressive personality, behavior, language and motor decline. These diseases create a level of functional impairment that significantly compromises the ability to carry out activities of daily living. There is currently no treatment and no cure, but there is hope. Research into these diseases may be a gateway to understanding and ultimately preventing, treating and curing more common neurodegenerative diseases like Alzheimer's and Parkinson's. CurePSP is the leading organization within this disease spectrum, providing support for patients, families and caregivers; awareness and education to healthcare professionals; and global research funding. Current research into prime of life diseases, especially progressive supranuclear palsy (PSP), is showing great promise for unlocking the secrets of neurodegeneration.

Our mission is to find a cure and improve the quality of life for those affected by cholangiocarcinoma (bile duct cancer). Founded in 2006, the Cholangiocarcinoma Foundation (CCF) is a global organization dedicated to curing cholangiocarcinoma (bile duct cancer) and enhancing patients’ quality of life. Through innovative methodologies, partnerships, and support programs, CCF connects patients and caregivers to resources, mentors, and support groups, while also fostering scientific discovery through an annual research fellowship program. CCF has grown to become the leading global resource in research, education, and public awareness.

To save and heal lives through organ and tissue donation.

Our mission is to provide high-quality, accessible mental health services to empower children, young adults, and families in the Chicago area. This will be accomplished through collaboration with local communities to identify the services they need, the building of a therapeutic milieu, and a focus on connection. We firmly believe in the idea of inclusivity and aim to maintain diversity of staff and clients as a priority.

To optimize philanthropy in support of the mission and future of the Children's Hospital of Chicago medical center.

Our mission: Save more lives by fueling the discovery and development of powerful immunotherapies for all types of cancer. After decades of investigation, scientists have unlocked the power of our body's own immune system to fight cancer. This class of treatments—called cancer immunotherapy—enhances a patient's immune system to identify and eliminate cancer cells, anywhere in the body. Established in 1953, the Cancer Research Institute (CRI) is a 501(c)(3) nonprofit organization that is dedicated to saving more lives by fueling the discovery and development of powerful immunotherapies for all types of cancer. We fund the most innovative clinical and laboratory research around the world, support the next generation of the field's leaders, and serve as the trusted source of information on immunotherapy for cancer patients and their caregivers. CRI's programs provide strategic support along the entire pathway of discovery, drug development, and patient support.

Bringing comfort and dignity as life nears its end.

Children's Cancer Research Fund is a national organization dedicated to curing childhood cancer by investing in the most effective research, collaborating with the most talented minds, inspiring and educating advocates worldwide to take action and supporting families.

A 501(c)(3) nonprofit organization raising awareness and funds for new global, cutting-edge research to find a cure for glioblastoma. The purpose of the Glioblastoma Research Organization is to provide financial support to doctors and researchers around the world, that are working on developing cutting-edge technologies and clinical trials through research, to increase the rate of survival in patients, and find a cure for this disease.

The Glioblastoma Foundation's mission is to transform the standard of care for Glioblastoma by funding new, more effective treatments, providing support to patients and families touched by the disease, and raising awareness of this rare and aggressive grade 4 brain tumor.

Approximately 3,000 children in Dallas go to sleep each night without a home of their own. We’re on a mission to help young children overcome the lasting and traumatic effects of homelessness. It is our vision that every child in our community has a home, a self-sufficient family and a foundation for success in school and life — and the clock is ticking. 90% of brain development happens by the age of five. Without intervention at this critical time, homeless children may suffer lifelong social, emotional and educational deficits. That’s where we come in. And YOU can help.

Fox Chase's mission is to reduce the burden of human cancer through the pursuit of knowledge in basic biological research; to conduct research specifically related to cancer causes, prevention, and treatment; and to apply this knowledge to the prevention of cancer and the treatment of cancer patients. Fox Chase has the oldest and third-largest cancer center support grant from the National Cancer Institute and is the oldest cancer specialty hospital in the nation. In January 2000, Fox Chase opened the nation's first facility devoted to comprehensive cancer prevention research. SEE ALSO this site's listings for the American Oncologic Hospital and the Institute for Cancer Research, which comprise the Fox Chase Cancer Center.