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The Lupus Foundation of America (LFA) is the oldest and largest national nonprofit voluntary health organization focused on improving the quality of life for people with lupus. Our unique dual mission serves the ongoing needs of people affected by lupus today while leading efforts to find a cure – from care to cure!  Through the national office in Washington, DC and a nationwide network of chapters, offices, support groups and community representatives, the LFA conducts programs of research, education, and advocacy.  The LFA is leading efforts to bring national attention and resources to bear upon lupus in order to shine a light on this medically underserved disease, accelerate the pace of medical research on lupus, build support for the needs of those affected by lupus, and elevate lupus to a place of prominence on the nation’s health care agenda.

The American Parkinson Disease Association (APDA) is the largest grassroots network dedicated to fighting Parkinson’s disease (PD) and works tirelessly to help the approximately one million with PD in the United States live life to the fullest in the face of this chronic, neurological disorder.

Families are at the heart of MDA's mission. We wake up every morning to create more hope and answers for families living with muscular dystrophy and related diseases that take away physical strength and mobility. We do this by finding research breakthroughs across diseases, caring for kids and adults from day one and empowering families with services and support in hometowns across America.

As the Drug Discovery Engine for ALS, the ALS Therapy Development Institute (ALS TDI) discovers and invents ALS treatments and partners to advance them into clinical trials. It is the first and largest nonprofit biotech focused 100% on ALS research. ALS TDI incorporates all aspects of drug discovery under one roof to find treatments as quickly as possible. Located in Watertown, MA, ALS TDI employs researchers with over 300 years of combined experience and expertise across all areas of drug discovery. ALS TDI is recognized as an international leader in preclinical and translational ALS research, and partners with pharmaceutical companies and biotechs around the world. Awarded the highest nonprofit rating – four stars – on Charity Navigator, ALS TDI spends 87 cents of every dollar raised on finding effective treatments and cures for ALS.

New Directions believes that people who have disabilities deserve the same opportunities in life that others expect and enjoy. Our profoundly enriching travel programs expand the self-esteem of every traveler. Whole new worlds of understanding open for both participants and the general population. Through these unique programs, people with disabilities are increasingly understood, appreciated and accepted as important and contributing members of our world. Changing the way the world views disability— one adventure at a time.

SBP solves the challenges facing at-risk communities by bringing the rigor of business and innovation to reduce risk, create resilient communities and streamline recovery.SBP works across the disaster preparedness and recovery continuum to drive direct impact and by sharing knowledge, people and funding. By taking a holistic approach, SBP shrinks the time between disaster and recovery in three intersecting ways—advocate, build and prepare.SBP advocates for policy and system change and advises state and local leaders to run disaster recovery programs more efficiently and effectively to create transformational change and scale impact.SBP builds resilient communities efficiently and effectively.SBP prepares individuals, communities and organizations to mitigate risk and speed recovery.

International Medical Corps is a global humanitarian nonprofit organization dedicated to saving lives and relieving suffering through health care training and medical relief programs. Established in 1984 by volunteer United States doctors and nurses, International Medical Corps is a private, nonpolitical, nonsectarian organization. Its mission is to improve the quality of life through health interventions and related activities that build local capacity worldwide. By offering training and health care to local populations and medical assistance to people at highest risk, and with the flexibility to respond rapidly to emergency situations, International Medical Corps rehabilitates devastated health care and economic systems and helps bring them back to self-reliance.

All Hands and Hearts provides community-inspired, volunteer-powered disaster relief.

About the CHOP Foundation: The Children's Hospital of Philadelphia Foundation is a charitable, tax-exempt organization benefiting the children's hospital of Philadelphia. As a nonprofit organization, children's hospital relies on donations to make a difference in the lives of children, to research better treatments for the future, to help families that cannot afford healthcare, and to provide quality of life programs and services.

PERIOD. is a global youth-powered non-profit that strives to end period poverty and stigma through advocacy, education, and service. PERIOD. equips and trains youth leaders with the tools and resources needed to end period poverty in their lifetime.

Trans Lifeline is a national trans-led 501(c)(3) organization dedicated to improving the quality of trans lives by responding to the critical needs of our community with direct service, material support, advocacy, and education. Our vision is to fight the epidemic of trans suicide and improve overall life-outcomes of trans people by facilitating justice-oriented, collective community aid.

Smile Train is an international children’s charity with a sustainable approach to a single, solvable problem: cleft lip and palate. Millions of children in developing countries with unrepaired clefts live in shame, but more importantly, have difficulty eating, breathing and speaking. Cleft repair surgery is simple, and the transformation is immediate. Our sustainable model provides training and funding to empower local doctors in 85+ developing countries to provide 100%-free cleft repair surgery in their communities. We use the “teach a man to fish” model focusing on training local doctors to perform cleft repairs in their communities. Those doctors then go on to train other doctors creating a long-term, sustainable system. Patients see their smile for the first time, parents cry tears of joy, lives and communities are changed forever. As a result of our efficiency and with the support of our donors and partners around the world, Smile Train has transformed the lives of more than one million children by giving them the power of a smile -- that's roughly 350 surgeries a day and 128,000+ every year.