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The mission of Doctors Without Borders/Médecins Sans Frontières (MSF) is to provide impartial medical relief to the victims of war, disease, and natural or man-made disaster, without regard to race, religion, or political affiliation. A non-profit, self-governed, member-based organisation, MSF's global reach is demonstrated by a presence in over 72 countries and territories with medical humanitarian projects, 9,904,200 medical consultations conducted by humanitarian teams, and 877,300 patients admitted to MSF hospitals or clinics around the world.

St. Jude Children's Research Hospital seeks to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of their founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay. St. Jude’s strives to be the world leader in advancing the treatment and prevention of catastrophic diseases in children, by providing outstanding patient care; conducting basic, translational and clinical research designed to elucidate biological mechanisms, understand disease pathogenesis, improve diagnosis, enhance treatment outcome, prevent diseases and minimize adverse consequences of treatment; and by educating health care and scientific research professionals. Treatments invented at St. Jude have helped push the overall childhood cancer survival rate from 20% to more than 80% since it opened more than 50 years ago.

Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

The Foundation's goal is to provide the ultimate environment for a child to become their best in all areas of their life, including academic, athletic, interpersonal skills, leadership, as a mentor, and someone willing to be mentored. They hope to arm children with a variety of ways to grow intellectually, spiritually, physically, and in their relationships with themselves and others. Their program is designed to go deeper into the subjects of life, excellence, and how to pursue happiness. In the end, our long-term goal is to help them become professionals in life, to find peace of mind, so they can share this wisdom with their families, friends, and communities as leaders and examples of extraordinary living and happiness.

The mission of the American Diabetes Association (the Association) is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. Diabetes is a disease in which the body does not produce or properly use insulin.  Insulin is a hormone that is needed to convert sugar, starches and other food into energy needed for daily life.  The cause of diabetes continues to elude the medical community, although research has shown that both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.

Autism Speaks is dedicated to promoting solutions, across the spectrum and throughout the life span, for the needs of individuals with autism and their families. We do this through advocacy and support; increasing understanding and acceptance of people with autism; and advancing research into causes and better interventions for autism spectrum disorder and related conditions. ​Through partnerships and collaboration, we are committed to: ​​Increasing global understanding & acceptance of people with autism Being a catalyst for life-enhancing research breakthroughs Increasing early childhood screening & timely interventions Improving the transition to adulthood Ensuring access to reliable information & services throughout the life span.

Founded in 2010 by Chef José Andrés, World Central Kitchen (WCK) is a nonprofit organization that is first to the frontlines providing fresh meals in response to crises. Applying their model of quick action, leveraging local resources, and adapting in real time, WCK has served more than 400 million nourishing meals around the world. When disaster strikes, WCK’s Relief Team mobilizes with the urgency of now to start cooking and serving meals to people in need. By partnering with organizations on the ground and activating a network of local restaurants, food trucks, or emergency kitchens, WCK serves comforting meals to survivors of disasters quickly and effectively. To support regional economies, WCK prioritizes purchasing local ingredients to cook with or distribute directly to families in need. WCK knows that good food provides not only nourishment, but also comfort and hope, especially in times of crisis. Learn more at wck.org.

The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson's disease through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson's today. The Foundation's focus is increasingly on clinical and translational research, crucial to making strides toward a cure and improved therapies for those living with Parkinson's today.

To eliminate Alzheimer's disease through the advancement of research; to provide and enhance care and support for all affected; and to reduce the risk of dementia through the promotion of brain health. The Alzheimer's Association is the world's leading voluntary health organization in Alzheimer's care, support and research. We value inclusivity, community, accountability, agility, and integrity. Our commitment to transparency, research, and diversity and inclusion helps to fulfill our vision: a world without Alzheimer's and all other dementia. In 2021, the Alzheimer's Association invested over $70 million in research, launched two new campaigns "Any Given Moment" and "More Time", and strengthened partnerships with faith-based communities. The Alzheimer's Association's powerful advocacy witnessed the Improving HOPE for Alzheimer's Act signed into law through the Association's leadership. At the beginning of the COVID-19 Pandemic, the Association's Walk to End Alzheimer's participants walked in small groups in their neighborhoods to raise $86 million.

Breast cancer is a complex disease with no simple solution. Research is the key to stopping it in its tracks. Founded in 1993 by Evelyn H. Lauder, the Breast Cancer Research Foundation (BCRF) is the largest private funder of breast cancer research in the world. We invest in the best minds in science—and foster cross-disciplinary collaboration—to examine every aspect of the disease from prevention to metastasis. Our approach accelerates the entire field and moves us closer to the answers we urgently need. We can’t stop now. Join us in fueling the world’s most promising research. With you, we will bring the end of breast cancer into focus. Learn more and get involved at BCRF.org.

To Write Love on Her Arms (TWLOHA) is a non-profit movement dedicated to presenting hope and finding help for people struggling with depression, addiction, self injury, and suicide. TWLOHA exists to encourage, inform, inspire, and invest directly into treatment and recovery. Among many of their impactful tools the “Find Help” tool offers 24-hour helplines for when immediate help is needed under the following specific categories: suicide, trauma, LGBTQIA+, veterans, eating disorders, depression + anxiety, self-injury and addiction. Through donations TWLOHA seeks to educate communities, provide hope and encouragement, and connect people to the help they deserve.