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The mission of Hearing Health Foundation (formerly called Deafness Research Foundation) is to prevent and cure hearing loss through ground breaking research.

The core mission of the IRSF is to fund research for treatments and a cure for Rett syndrome while enhancing the overall quality of life for those living with Rett syndrome by providing information, programs, and services. In 1983, a small dedicated group of parents whose children had Rett syndrome formed the first non-profit to focus exclusively on Rett syndrome – International Rett Syndrome Association (IRSA). In 2007, IRSA and Rett Syndrome Research Foundation (RSRF) consolidated resources to better serve families and maximize research investments toward a cure. The International Rett Syndrome Foundation (IRSF) emerged with a mission to accelerate research and empower families that builds upon these foundations’ pioneering work toward care and cure. We are walking this journey with you. IRSF is comprised of parents and friends of those diagnosed with Rett syndrome. We are dedicated to empowering families with the latest medical information, offering meaningful support and resources, and advocating for all those living with Rett syndrome. Our strategy is simple but powerful: improve care today and create treatments for tomorrow. IRSF is committed to a full-spectrum approach, providing solutions for everyone living with Rett syndrome. We do this by investing in innovative research, working to build a robust treatment pipeline, and removing barriers to ensure clinical trial success.

The Lymphoma Research Foundation's mission is to eradicate lymphoma and serve those touched by this disease.

The American Cinematheque was created to 1) honor and promote America's indigenous art form: the Moving Picture; 2) present the full range of film and video, not otherwise available, to the widest possible audience; 3) establish a forum for an on-going dialogue between filmmakers and their adiences, 4) provide high profile exhibition facilities for other independent film and video festivals and organizations; and 5) encourage and support new talent by creating a showcase for their work.

With the success of the Salk vaccine in the mid 1950s, the March of Dimes turned its focus on birth defects, low birth weight and infant death. Over the past 75 years, March of Dimes' cutting edge research and innovative programs have saved millions of babies from death or disability. We are committed to educating medical professionals and the public, supporting research, providing comfort and support to families in NICUs, and advocating for moms and babies. All mothers and babies deserve access to the tools they need for the success of their families, so that the future is brighter for all. Every Mom. Every Baby.

When a child is born with a severe hearing loss, the impact on the parents and the problems facing the child are staggering. John Tracy Clinic is a place where parents of young deaf children can find hope, guidance and encouragement. Its purpose is to train and support parents in helping their young deaf children develop the communication skills necessary to reach their full potential. The Clinic was founded by Louise Tracy, wife of actor Spencer Tracy, whose son, John, was born deaf.

The Dian Fossey Gorilla Fund International is dedicated to the conservation and protection of gorillas and their habitats in Africa. We are committed to promoting continued research on their threatened ecosystems and education about their relevance to the world in which we live. In collaboration with government agencies and other international partners, we also provide assistance to local communities through education, training and economic development initiatives.

It Gets Better envisions a world where all LGBTQ+ youth are free to live equally and know their worthiness and power as individuals. The organization's mission is to uplift, empower, and connect lesbian, gay, bisexual, transgender, and queer youth around the globe. It reaches millions of young people each year through inspiring media programming, educational resources, international affiliates in 19 countries, and access to an arsenal of community-based service providers. In 2010, LGBTQ+ people and their allies all over the world uttered three words that would give rise to a global movement — it gets better. A wildly successful social media campaign was born, with more than 70,000 people sharing their stories to provide hope and encouragement to young LGBTQ+ people.

The Tuberous Sclerosis Alliance is dedicated to finding a cure for tuberous sclerosis complex while improving the lives of those affected.

UMDF's mission is to promote research and education for the diagnosis, treatment and cure of mitochondrial disorders and provide support to affected individuals and families.

Pencils of Promise (“PoP”) is a 501(c)(3) nonprofit organization that believes every child deserves access to quality education.  They create schools, programs and global communities around the common goal of education for all.

THE ARCHER SCHOOL FOR GIRLS IS AN EDUCATIONAL COMMUNITY THAT SUPPORTS AND CHALLENGES YOUNG WOMEN TO DISCOVER THEIR PASSIONS AND REALIZE THEIR TRUE POTENTIAL BY A) PROVIDING A RIGOROUS, INTEGRATED COLLEGE PREPARATORY CURRICULUM THAT FOSTERS CRITICAL THINKING AND INTELLECTUAL CURIOSITY