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Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

TransSOCIAL, Inc.'s mission is to expand safe and affirming resources for our Trans, gender expansive and Intersex community. We are Trans-led and provide direct services including legal name and gender marker change assistance, ID updates, affirming medical and mental health referrals, peer support groups and social events, and TLGBQ+ Cultural Sensitivity Training to businesses and organizations to help them create safe spaces for our community.

It is the mission of Shriners Hospitals for Children to: -Provide the highest quality care to children with neuromusculoskeletal conditions, burn injuries and certain other special health care needs within a compassionate, family centered and collaborative care environment -Provide for the education of physicians and other health care professionals -Conduct research to discover new knowledge that improves the quality of care and quality of life of children and families. This mission is carried out without cost to the patient or family, and without regard to race, color, creed, sex or sect.

The American Foundation for Suicide Prevention is dedicated to saving lives and bringing hope to those affected by suicide. AFSP creates a culture that’s smart about mental health through education and community programs, develops suicide prevention through research and advocacy, and provides support for those affected by suicide. AFSP has local chapters in all 50 states with programs and events nationwide.

Since 1974, Duke Ellington School of the Arts has provided equitable access to a life-changing arts education for the District's talented youth, regardless of background or ability to a pay. Ellington is the only DC public high school to offer a dual curriculum encompassing professional arts training and academic enrichment. It has a 4-star rating and is one of the highest ranked public high schools in DC with 97% of students graduating on-time and 95% of graduates enrolling in institutions of higher-learning, often receiving over $10 million in scholarships. Our students’ deep commitment to the arts empowers them to succeed academically. The Ellington Fund is a non-profit organization and the the charitable arm of the Duke Ellington School of the Arts. All donations are tax-deductible to the full extent of the law.

No Kid Hungry is a national campaign run by Share Our Strength, a nonprofit working to solve problems of hunger and poverty in the United States and around the world. After 25 years of successfully investing in local nonprofits and helping find the best approaches to eradicating poverty and hunger, Share Our Strength launched No Kid Hungry in 2010. Though ending childhood hunger is the organization’s primary focus, Share Our Strength continues to invest in and develop other campaigns.

The mission of the American Diabetes Association (the Association) is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. Diabetes is a disease in which the body does not produce or properly use insulin.  Insulin is a hormone that is needed to convert sugar, starches and other food into energy needed for daily life.  The cause of diabetes continues to elude the medical community, although research has shown that both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

The National Multiple Sclerosis Society's mission is to cure multiple sclerosis while empowering people affected by multiple sclerosis (MS) to live their best lives. The organization pledges to accelerate cures through global leadership, and improve access to personalized, affordable, high-quality MS healthcare. It empowers people affected by MS to solve everyday challenges and strengthens the MS movement through more and deeper connections.

Through education and outreach we support those affected by Lewy body dementias, and promote research for a cure.

The Pancreatic Cancer Action Network (PanCAN) is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer. Our mission is to take bold action to improve the lives of everyone impacted by pancreatic cancer by advancing scientific research, building community, sharing knowledge, and advocating for patients. PanCAN has invested more than $149 million in research since 2003. In the past year our nationwide PurpleStride community raised $11.8 million to fund our critical research and programs and services for patients. We have more than 700 PanCAN volunteer leaders driving local community action in our nationwide moment.

One Tree Planted is a 501c3 non-profit organization dedicated to global reforestation. The organization makes it simple for anyone to help the environment and support healthy forests. All of One Tree Planted's projects are guided by the following six pillars of reforestation: air, water, biodiversity, social impact, health and climate. To achieve their impact, they collaborate with over 266 incredible reforestation partners, make an impact in over 80 countries and communities, and have planted over 100,000,000 trees.

The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.